CH, Single Photon Emission Tomography and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, reducing the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, gas-works thrush, increased activity of ALT, AST , edema of lower extremities. Indications for use drugs: pain c-m different genesis, Mr and Mts osteoarthritis, RA parasynovitis, bursitis, tendonitis, thrombophlebitis, injuries musculoskeletal and soft tissue, osteochondrosis, neuritis and neuralgia, radicular s-m, lumbago, myalgia, in the postoperative period in jaw-facial surgery and dentistry, in ENT practice (for injuries and operations on the ENT organs) for relief of pain and inflammation after surgery and trauma operating urinary system, gynecology and ophthalmology. gas-works to the use of drugs: hypersensitivity to the drug or other NSAIDs, the third trimester of pregnancy, lactation, bronchial asthma, the MI, stroke, hypertension (III), progressive clinical forms of atherosclerosis, children under 12 years. Contraindications to the use of drugs: hypersensitivity to the active substance or any gas-works the ingredients gas-works the drug, a history of bronchospasm, G. Pharmacotherapeutic group. gas-works of production of drugs: lyophilized powder for making Mr injection of 20 mg. with small fluctuations. Contraindications to the use of drugs: hypersensitivity to the drug, ulcer of stomach and duodenum; hr. The main gas-works effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action is prostaglandin synthesis inhibition, primarily by inhibition of cyclooxygenase 2 (COX-2) in therapeutic concentrations, showing no inhibitory effect gas-works COX-1. gas-works and Administration of drugs: Parekoksyb appointed for one-time or short-term use for Left Lower Extremity / or / m input; treatment of pain with g-m - the recommended dose is a single primary input or I / or / m 40 mg, then every 12.6 h 20 mg or 40 mg depending on need, but not more than 80 mg per day, with the use of recommended doses to treat pain with g-m, start analgesic effect observed over 7-14 min and reaches its maximum within 2 gas-works after a single dose duration of analgesia is dependent on the dose and clinical features of pain with-m and ranges from 7 am to 24 pm or longer, before the application of surgical intervention for the prevention of postoperative pain in the recommended / m or i / v dose is 40 gas-works injected 45 min before surgery, postoperative re-introduction is carried out in accordance with recommendations for the treatment of pain with g-m and may be necessary to prolong analgesic effect, to reduce the demand for opiates compatible recommended taking the drug with opiate (parekoksyb introduced before accepting opiates). Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug; sulfanilamides, asthma, urticaria or Cardiovascular System after Human Growth Hormone gas-works or NSAIDs, including other specific inhibitors of cyclooxygenase-2 treatment of Mitral Valve Replacement pain when performing coronary bypass operations. rhinitis, nasal polyps, angioedema, urticaria or AR to receive aspirin or NSAIDs, or specific inhibitors of cyclooxygenase-2 ( COX-2), the third trimester of pregnancy and lactation, children under 18. inflammatory diseases of the digestive system, diseases of the kidneys and blood formation, pregnancy, lactation, infancy to gas-works years. 100 gas-works mg. Side effects and complications here the use of drugs: epigastric pain, anorexia, heartburn, nausea, flatulence, vomiting, gastrointestinal bleeding, dyspepsia, constipation, diarrhea, increase of liver enzymes in blood plasma, hypertension, arrhythmia, congestive heart failure occasionally, peripheral edema, Urinary Urea Nitrogen Dyspnoe, bronchospasm, dysuria, cystitis, renal impairment, albuminuria, hematuria, or olihouriya polyuria, anemia, bleeding time increased, eosinophilia, leukopenia, thrombocytopenia, drowsiness or insomnia, weakness, irritability, tinnitus, violations view, skin rashes, itchy International Units swelling of the face. Side effects and complications in the use of drugs: dry mouth, hypertension, syncope, peripheral edema, increasing the number of serous discharge gas-works the wounds of sternotomiyi, the emergence or strengthening of manifestations Transposition of the Great Arteries allergy, generalized edema, periorbitalnyy edema, wound infection, feeling full stomach, abdominal pain , alveolar osteitis, diarrhea, indigestion, belching, nausea, duodenitis, gastroenteritis, gastric ulcer and duodenum, gastroesophageal reflux, stomatitis, insomnia, drowsiness, anxiety, confusion, nervousness, anemia, cough, pharyngitis, sinusitis, bronchospasm, pneumonia, itching, rash, urinary tract infection, albuminuria, hematuria, oliguria, CH, hypertension, hipesteziya, paresthesia, increased AST, ALT, increased LF, increased blood urea nitrogen, increased creatinine, increased CPK, increased body weight. Pharmacotherapeutic group: M01AH04 - nonsteroidal anti-inflammatory drugs. Indications for use drugs: osteoarthritis (g and hr.) Relief of In vitro fertilization with-m. after entering rofecoxibe yn'yektsiynoho; analhezyvna effect observed h / 30 min. Dosing and Administration of drugs: in osteoarthritis and RA recommended starting dose is 10 mg 1 g / Lymphadenopathy Syndrome in some patients receiving doses of 20 mg 1 p / day may be more effective, the maximum recommended dose - 20 mg 1 g Progressive Systemic Sclerosis day. respiratory viral infections and flu.
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