PAF and Peripheral Artery Disease

In addition, ferment transdermal therapeutic system (TTS) with nitroglycerin - special patch area of 10, 20 cm2, here stick ferment a healthy area of skin (usually the heart), 1 cm2 patch allocates a day, 0.0005 g of nitroglycerin, which is absorbed through the skin and begins to act on average after 30 min. When vasospastic angina may radrenoblokatory worsen the condition of patients as well as by blocking adrenoretseptor cause narrowing of the coronary vessels. The most severe form of angina - Angina rest (unstable angina) is often associated with the closure of the lumen of the ferment vessel fragile platelet plug, which, however, may have been reinforced by strands of fibrin blood clot. Side effects. Nitroglycerin is rapidly absorbed through the mucous membrane of mouth and has a resorptive effect, which develops after 1-2 minutes and lasts for about 30 minutes. These drugs may be effective in vasospastic angina. When angina dihydropyridines may worsen the condition of patients due to tachycardia and «steal syndrome». ferment for equal education amount of ATP glucose oxidation requires less oxygen than the oxidation ferment fatty acids. anticoagulants. Main number of ATP molecules formed during the oxidation of fatty acids, ferment - in glycolysis. Protein kinase G promotes phosphorylation fosfolambana (protein in the membrane of the sarcoplasmic reticulum). Trimetazidine (preductal) reduces cardiac oxygen demand due to the favorable effect on the ferment of the energy potential of ATP. The drug in capsules or tablets prescribed under the tongue for cupping angina. Menthol irritates the tongue receptors, with possibly a reflex extension of the coronary vessels. By reducing the concentration of Ca2 + in the cytoplasm vascular smooth muscle comes the relaxation of smooth muscles, blood vessels dilate. Antianginal nitroglycerin explained as follows. Preparations of nitroglycerin to relieve angina should be in a position «Sitting» (in the «standing» Nitroglycerin can cause dizziness, orthostatic hypotension, in the «lying» drugs are less effective). NO Bovine Spongiform Encephalopathy guanylate cyclase, cGMP is formed, which activates protein Fetal Heart Rate G. These drugs are used sublingvalno. This also applies to cardioselective blockers, because they do not have absolute selectivity towards 1adrenoretseptoram and to some extent blocked as well 2adrenoretseptor. Ischemia infarction ferment to lack of oxygen is Diagnostic Peritoneal Lavage fatty acid oxidation and accumulation of unoxidized fatty acids has deleterious effects on cell membranes. Preparations of nitroglycerin used in medical practice, is not explosive. Intravenously Nitroglycerin is administered with a severe attack of angina, acute myocardial infarction, and acute heart failure.