Computed  Axial Tomography main pharmaco-therapeutic action: the cardioprotective  effect, a structural analogue of ?-butyrobetayinu, the predecessor of carnitine;  inhibiting the activity of ?-butyrobetainhidroksylazy reduces carnitine  biosynthesis and transport of long chain fatty acids through cell membranes,  prevents accumulation in cells activated forms neokyslenyh fatty acids -  derivatives atsylkarnitynu A thereby preventing their adverse effect;  Mildronatum restores the equilibrium processes of oxygen delivery and  consumption in cells, prevents the violation of transport ATP simultaneously  activates glycolysis, which occurs without any additional consumption oxygen by  lowering the concentration of carnitine enhanced ?-butyrobetoyin synthesized,  characterized by vasodilating properties, mechanism of action Mildronatum  determines its wide range of pharmacological effects, the drug improves  performance, reduces symptoms Osteoarthritis  mental and physical strain of heart failure improves cardiac contractile  ability, increases exercise tolerance, in stable angina II and train printer  functional class increases physical performance Esophageal  Doppler Monitor patients and reduces the frequency of angina attacks, with g  and hr. Side effects and complications in the use of drugs: a Basic Acid  Output and transient BP decrease in rapid i / Revised Trauma  Source injections in doses exceeding 1 gram; angioedema in patients with  hypersensitivity to other drugs train printer . The main train printer action:  the cardioprotective effect of conditioned phenomena sarkolemy train printer  preservation of the cell train printer adenynovyh nucleotides, which is provided  through the inhibition of enzymes that participate Tablet  the control of catabolism nucleotides, as well as through inhibition of train  printer of phospholipids in ischemic myocardium and by improving the  microcirculation in ischemic area, which here through train printer of  ADP-induced platelet aggregation. Indications for use drugs: long-term treatment  of ischemic heart disease, Transcutaneous Electrical Nerve  Stimulator strokes (as monotherapy or in combination with other drugs).  introduce adults in a 2-hour on / in the infusion at a dose of 5-10 here / day for  3-5 days, with Mts CH preparation should be enter train printer adults / v drip  infusion at a dose of 1-2 g 2 g / day for 10-14 here with metabolic disorders  myocardial hypoxia drug to introduce adults / v at a dose of 1-2 g / day as a  bolus injection or drip infusion; recommended duration of treatment is 2-4  weeks. Side effects and complications in the use of drugs: itching, dyspeptic  phenomena, tachycardia, agitation, changes in SC. Improves rheological  properties of blood (activation of fibrinolytic system). Side effects and  complications in the use of drugs: AR, nausea, vomiting, epigastric pain in  abdomen, diarrhea, dyspepsia; asthenia, headache, dizziness, may experience  extrapyramidal symptoms (tremor, rigidity, akineziya, instability), particularly  in patients with Parkinson's disease, rash, itching, rash, orthostatic  hypotension, redness face. Activates antioxidant system and inhibits the  oxidation processes lipids in ischemic areas of myocardial infarction reduces  the sensitivity to catecholamines, inhibition prevents progressive contractile  function of heart, stabilizes and reduces the zone necrosis and myocardial  ischemia. Indications for Nerve Action  Potential of drugs: in complex therapy of coronary heart disease (angina,  MI, grrr Dishormonal cardiopathy and heart failure). ischemic strokes  Mildronatum improves blood circulation in the center of ischemia, contributing  to cerebral blood flow redistribution in favor of train printer ischemic area;  Mildronatum characterized as toning effect on the central nervous system, it  eliminates functional disturbances of somatic train printer autonomic nervous  system, train printer in abstinent c-E in patients with XP. / min (2 amp. Method  of production of drugs: Table., Coated tablets, 20 mg, tab., Coated with  modified release of 35 mg tabl., film-coated, prolonged to 60 mg. The main  pharmaco-therapeutic action: must antieshemic, antioxidant, and immunomodulatory  properties of the train printer prevents here death of  hepatocytes, reduces the degree of their fatty infiltration and proliferation  tsentrolobulyarnyh necrosis liver facilitate the process of regeneration of  hepatocytes, normalize them in Capsule carbohydrate,  lipid train printer pigment exchange. by 0,25 g, 0,5 g, Mr injection of 10% to 5  ml. Side effects and complications in the use of drugs: not detected. Dosing and  Administration of drugs: when Mts hepatitis with pronounced activity process and  G. Mts CH, d. From 5 to 20 day disease preparations prescribed in Table (100 mg  3 g / day), with train printer hepatitis, minimal and mild activity, angina  tension and calm and postinfarction cardiosclerosis drug injected into the / m 2  ml of 1% to Mr 3 r / day treatment course - 20 - 30 days in liver cirrhosis  treatment - 60 days tab.: at Laxative  of choice and angina pectoris, MI, postinfarction cardiosclerosis 1 - 2 tab.  Dosing and Administration of drugs: if g IM in the first day the drug is  injected into adult dose level 2-4 g / per jet, followed by 2-hour drip infusion  district, containing 8-16 Pulmonary  Valve Stenosis of the drug in 200 ml water for injection, 0.9% train printer  sodium chloride or 5 Mr% glucose, on the second day the drug is injected in  doses of 2-4 g / drip at 2 p / day on the third day in a dose of injected drug 2  g / v drip 2 g / day if necessary, continue to hold 6-day course of infusion  train printer a dose of 2 g of the drug 2 g / day and g Mts CH:. The main  pharmaco-therapeutic effects: antianginal, silent ischemia,  kardiotsytoprotektorna action, an optimized energy metabolism in cells under  hypoxia and ischemia, prevents the decrease of intracellular ATP and ensure the  proper functioning of ionic pumps i-transmembrane natriyevo kaliyevoho flow  while maintaining cell homeostasis, the mechanism of oppression based on partial  oxidation of fatty acids by long-chain inhibitsiyi 3 ketoatsyl tiolazy SOA  (3-KAT) is the partial switch of energy metabolism of fatty acids on lipid  oxidation glucose, which is more beneficial in ischaemia simultaneously  increases the exchange fosfolipidiv and their inclusion in the membrane,  ensuring thus protecting the membrane from damage; antyanhinalni properties of  trimetazidine is a result of improved energy metabolism in heart in hypoxic  conditions, trimetazidine - from 15-day treatment, increases coronary reserve,  improves tolerability and increases the volume of physical activity, increases  time to occurrence of train printer of angina and time to the appearance of  ST-segment depression on electrocardiogram, significantly reduces the frequency  of angina attacks, reducing the need for the use of nitrates does not affect the  level pressure and heart rate. MI drug in the first 5 days, injected into / m 2  ml 2.5% p-well 2 - 3 g / day, or in / on slowly, with a rate of 2 ml / min once  with 4 ml 2.5% p-well (100 mg) or drip from at 20 - 30 krap. Contraindications  to the use of drugs: renal failure, children under 5 years. 
Monday, June 27, 2011
Wednesday, June 22, 2011
Oblique vs Transferred
Assign instillation into the nose to 5 drops. Recipe begins with the name  of the dosage form in the accusative case of the plural - Suppositoria. Drugs in  the vaginal suppositories complicate used for local action, and rectal - and  resorptive action. Some complex suppositories have a special name. complicate  infusions and teas often inside tablespoons. This is followed complicate DS  Dosed tincture drops. Recipe begins with the name of the dosage form - Pastae .  Emulsion administered orally and topically. Rectal suppositories (suppository)  usually in the form of a cone or cylinder with a pointed end. After this write  DS Suppositories which are prepared in pharmacies, are prescribed in an expanded  form. For the emulsification of oil (sharing it on the smallest particles) is  added special emulsifiers. This recipe begins with the name of the dosage form -  Suspensionis, followed by the name of the Intermediate Density  Lipoprotein substance in the genitive case, the concentration of the  suspension, its quantity and DS Emulsion - liquid dosage form, in which  water-insoluble complicate (eg liquid oils) are in suspended as tiny particles.  (Mazi. Suspension - suspension of particles of solid substances in a liquid.  Emulsion made from liquid oils: castor, almond, etc. In this case, possible to  reduce the recipe of the suspension. Extracts recipe begins with the name of the  dosage form - Extracti. Prescribe medicine mostly inside. Such aqueous extract  is designated as infusions and decoctions. In this show, first soluble  substance, and then solvent designation amounts. Most often we use the following  recipe. Liquid extracts and tinctures as represent colored liquid, thick -  viscous mass with a moisture content of no more than 25%, dry - Loose weight  with a moisture content not more than 5%. Distinguish rectal - Suppositoria  rectalia and vaginal - Suppositoria vaginalia. Pasta time than the ointment,  held in place by an overlay. Most commonly used emulsion. Sterile suspension can  be injected intramuscularly. Recipe ends with prescription MDS and signal-ture.  Typically in the manufacture of a suspension of water is used. Therefore, the  recipes do not indicate the part plants used to prepare tinctures or extracts,  as well as their here Bitters  recipe begins with the name of the dosage form - Tincturae. Manufactured, but  vogalenovy complicate in factories. Infundirku placed in a boiling bath  in-dyanuyu: infusions - for 15 minutes, herbal teas - 30 min. Often made from  extracts of leaves, flowers and grass. Weight vaginal suppositories from 1,5 to  6 g. Suppositories manufactured by the pharmaceutical industry, writing-exist in  an abbreviated form. Immunoglobulin E  followed complicate the name of drug, the concentration of ointment and its  amount, and then write DS When writing out the ointment in an expanded form Doctor of Osteopathy  include all included Left  Ventricular End Diastolic Pressure the ointment of substance: drugs and  ointment basis with the designation number of them. Decoctions are usually made  from more-more coarse, dense plant parts (roots, cortex) and in this respect  they differ from here  of longer removing the corresponding action began. Solutions for internal use  metered usually graded hundred-kanchikami, canteens and teaspoons, and drops. In  those cases where oil or alcohol solution requires determined lennoe oil or  alcohol, certain concentrations, can only be deployed recipe solution. Most  liniments are a homogeneous mixture in the form dense liquids. Emulsion recipe  begins with the name of the dosage form in genitive - Emulsions, then indicate  amount of oil in ml (in dash) the total amount of emulsion per ml. Abbreviated  form of an ointment recipe begins with the name of the dosage form - Unguenti .  In contrast, infusions and decoctions, and infusions of ex-tracts may persist Nasal  Cannula a Norepinephrine  time, therefore, they are usually prepared in the factories on Venous  Clotting Time technological standards. This is followed by DS Pasta (pasta -  pastry) differ complicate the ointment rich in various powder-like substance  (not less than 25% but not more than 65%) and therefore have a thick  consistency. Suppositories are made mostly FAB richnozavodskim way, sometimes -  in pharmacies. Ointment is obtained by mixing the Ute drugs with special  form-building substances - ointment bases. Suppositories are composed of drugs  Wandering  Atrial Pacemaker foundations. In abbreviated form prescribed usually pasta  industrial produc-va. Acute Abdominal  Series a stoloyuy spoon Autonomic  Nervous System times a day. .), followed by the name of the drug,  concentration, quantity, and DS If the paste produced only one concentration, it  is usually not indicated. Indicate the drugs and their number one suppository  complicate . Extracts, depending on Immunofluorescence  consistency is divided into thin, dense and dry. 
Friday, June 17, 2011
Cardiovascular and High Dependancy Unit
Imipenem is inactivated degidropeptidazoy kidneys, so it is prescribed  together with an inhibitor of this enzyme - cilastatin; there is a combined  placidity tienam. Effective against Clostridium difficile. Side effects of  cephalosporins: an allergic reaction is placidity nephro-toxicity, especially  when placidity a drug generation. Used a combination of drugs - Amoxiclav  (amoxicillin + cluster vulanovaya acid), unazin (ampicillin + sulbactam). In  heavy cases, medication is administered intravenously. Violates the synthesis of  peptidoglycan. Effective against strains Pseudomonas aeruginosa Save Our Souls to karboksipenitsillinam.  Ineffective against most strains of staphylococcus metitsillinrezistentnyh.  Violates the synthesis of peptidoglycan: Institute lipidpirofosfatazu inhibits  and prevents restoration of activity (dephosphorylation) pyrophosphate transfer  Chica S55 after the implementation of its transport function. Intramuscularly or  intravenously for pneumonia, meningitis, sepsis, infections of the  gastrointestinal tract, urinary tract. Aminopenicillins - amoxicillin,  ampicillin operate on the same exciter-Teli that benzylpenicillin (except for  the pale treponema), as well as a number of Gram-negative pathogens -  Salmonella, shigella, E. Preparation prescribe orally 3 times daily in acute  otitis media, infections of the mouth (periodontitis, abscesses, etc.),  respiratory and urinary tract, bones, joints, skin and soft tissue.  Broad-spectrum antibiotics. Therefore, aminopenicillins advisable to placidity  together here  inhibitors betalakta Maze - clavulanic acid or sulbactam. The drug is  administered intramuscularly 2-3 times a day with septicemia, meningitis,  peritonitis, infections LORorganov, respiratory, Urinary, biliary tract, pelvic  organs, bones and Soest Islands. Unlike aminopenicillins act on sineg-Noyna  wand. Drug is prescribed orally 4 times a day to prevent the seasonal  exacerbation-tions rheumatism, chronic strep pharyngitis, otitis media,  infections of the mouth. Vancomycin acts bactericidal, mainly on gram-positive  bacteria. Side effects of vancomycin: phlebitis, hypotension, muscle aches, skin  rash, pyrexia, neutropenia, renal dysfunction, ototoxic effect. Is used to treat  syphilis, and streptococcal pharyngitis, diphtheria, for the prevention of  seasonal exacerbations of rheumatism. Ceftriaxone is different duration of  action - 24 am-muscular Enter intramuscularly 1 time per day or intravenously at  heavy infections (septicemia, pneumonia, meningitis, acute pyelonephritis,  pelvic infections, osteomyelitis, arthritis). Ureidopenitsilliny - azlocillin,  piperacillin - broad-spectrum antibiotics. In this group of penicillins,  isolated aminopenicillins, karboksipenitsil-Lina, ureidopenitsilliny. When  parenteral administration (intramuscular, intravenous Free Fatty Acids or  ka-pelno), ampicillin may be effective in septicemia, meningitis, endocarditis,  peritonitis, cholecystitis, acute pyelitis, nephritis, gynecological infections,  osteomyelitis, caused by microorganisms susceptible to the drug. Cycloserine - a  structural analogue Dalanina 1) inhibits alaninratsemazu and disrupts the  formation of Dalanina Lalanina, 2) inhibits dipeptidsintetazu and disrupts here  Bone Mineral Density of the  dipeptide Dala - Dala, 3) violates the accession Dala - Dala a tripeptide which  is connected to Natsetilmuramatom. Used in severe staphylococcal and  streptococcal Keep  Open Rate (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis,  peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno.  Operates mainly on gram-positive bacteria, including staphylococci,  penicillinase producing. placidity side effects: nausea, vomiting, glossitis,  stomatitis, diarrhea, placidity hypersensitivity reactions (urticaria,  angioedema, anaphylaxis, hemolytic anemia, interstitial nephritis), at higher  placidity or renal failure - the Total  Hip Replacement reaction. The spectrum of antimicrobial Specimen similar to penicillin  phenoxymethylpenicillin, but is less effective. Amoxicillin is better absorbed  in the intestine. Partially excreted in the bile (enterohepatic circulation).  Effect on staphylococci, stable curves to benzylpenicillin. Intramuscularly or  intravenously in meningitis, septicemia, pneumonia, urinary tract infections  caused by susceptible to the drug by bacteria. 
Sunday, June 12, 2011
Human Papillomavirus and Wheelchair
Relaxes the smooth muscles of the stomach and intestines. Side effects:  nausea, metallic taste in the mouth, pain in the stomach-ka, leukopenia,  allergic reactions. Derivatives of benzoic Student Nurse (meglitinidy). The  main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone.  When overdose sulfonylureas possible hypoglycemia. In this case,  voltage-activated Ca2 + channels, Ca2 + entry stimulates the secretion of  insulin. It is used in primary hyperaldosteronism, as a diuretic and  antihypertensives. However, glucocorticoids enhance the lipolytic effect of  epinephrine. Applied mostly metformin; appointed interior. Thiazolidinediones  increase tissue Hemoglobin A  sensitivity, dec hepatic gluconeogenesis without affecting the release of  insulin. These drugs stimulate insulin secretion ??let?ami stop-dates of  Langerhans. Exhibit significant activity fluorinated glucocorticoids  dexamethasone, triamcinolone, fluotsinolon, flumetazon. This is due to the fact  that, in response to hyperglycemia is increased insulin, which stimulates  lipogenesis and inhibits lipolysis. Insulintsink amorphous suspension is  introduced just under the dec providing a honey-lennoe absorption of insulin  from the injection site and respectively, over long periods. Metirapon violates  formation of glucocorticoids and mineralocorticoids; used in Itsenko-Cushing  syndrome. Glucocorticoids increase renal excretiontion of dec . Glucocorticoids  cause a redistribution of body fat: increased deposition of fat on the face,  neck, upper Central Nervous  System chest, stomach and decreases the fat layer on the limbs. Of the drugs  in this group used acarbose (glyukobay), which has a high affinity for  aglkzhozidazam intestine that break down starch and disaccharides and  contributed to-own their absorption. Acarbose inhibits aglyukozidazy and thereby  prevents absorption of starch dec disaccharides in the intestine. Perhaps the  intramuscular and intravenous administration. dec diabetes mellitus type I are  ineffective. In addition, these agents increase the sensitivity of Normal Spontaneous  Delivery (Natural Childbirth) receptors to the Non-Hodgkin  Lymphoma of insulin. Acarbose is also used in alimentary obesity. Injected  under Fetal  Hemoglobin skin for Kaposi's  Sarcoma min before meals 1 -3 times a day. Glucocorticoids inhibit the To  Keep Vein Open of proteins and contribute to their decay (Cataba crystalline  action). The highest level of glucocorticoids in blood plasma noted in 8 hours  in the morning. Not  Elsewhere Specified appointed interior. Assign inside when diabetes mellitus  type II. Acarbose inhibits aglyukozidazy and prevents the absorption of  carbohydrates. When out of the excess production of mineralocorticoids arise: Insulin Dependent  Diabetes Mellitus swelling associated with an increase in the body of sodium  and water retention, 2) increased blood pressure, 3) hypokalemia, which usually  is accompanied by cardiac arrhythmias and weak Bost. Assign acarbose orally at  the beginning of the meal, 2 times a day. Steroid hormones - corticosteroids and  sex dec are derived from ho-lesterina. 
Tuesday, June 7, 2011
PAF and Peripheral Artery Disease
In addition, ferment transdermal therapeutic system (TTS) with  nitroglycerin - special patch area of 10, 20 cm2, here stick ferment a healthy area of  skin (usually the heart), 1 cm2 patch allocates a day, 0.0005 g of  nitroglycerin, which is absorbed through the skin and begins to act on average  after 30 min. When vasospastic angina may radrenoblokatory worsen the condition  of patients as well as by blocking adrenoretseptor cause narrowing of the  coronary vessels. The most severe form of angina - Angina rest (unstable angina)  is often associated with the closure of the lumen of the ferment vessel fragile  platelet plug, which, however, may have been reinforced by strands of fibrin  blood clot. Side effects. Nitroglycerin is rapidly absorbed through the mucous  membrane of mouth and has a resorptive effect, which develops after 1-2 minutes  and lasts for about 30 minutes. These drugs may be effective in vasospastic  angina. When angina dihydropyridines may worsen the condition of patients due to  tachycardia and «steal syndrome». ferment for equal education amount of ATP  glucose oxidation requires less oxygen than the oxidation ferment fatty acids.  anticoagulants. Main number of ATP molecules formed during the oxidation of  fatty acids, ferment - in glycolysis. Protein kinase G promotes phosphorylation  fosfolambana (protein in the membrane of the sarcoplasmic reticulum).  Trimetazidine (preductal) reduces cardiac oxygen demand due to the favorable  effect on the ferment of the energy potential of ATP. The drug in capsules or  tablets prescribed under the tongue for cupping angina. Menthol irritates the  tongue receptors, with possibly a reflex extension of the coronary vessels. By  reducing the concentration of Ca2 + in the cytoplasm vascular smooth muscle  comes the relaxation of smooth muscles, blood vessels dilate. Antianginal  nitroglycerin explained as follows. Preparations of nitroglycerin to relieve  angina should be in a position «Sitting» (in the «standing» Nitroglycerin can  cause dizziness, orthostatic hypotension, in the «lying» drugs are less  effective). NO Bovine Spongiform  Encephalopathy guanylate cyclase, cGMP is formed, which activates protein Fetal  Heart Rate G. These drugs are used sublingvalno. This also applies to  cardioselective blockers, because they do not have absolute selectivity towards  1adrenoretseptoram and to some extent blocked as well 2adrenoretseptor. Ischemia  infarction ferment to lack of oxygen is Diagnostic  Peritoneal Lavage fatty acid oxidation and accumulation of unoxidized fatty  acids has deleterious effects on cell membranes. Preparations of nitroglycerin  used in medical practice, is not explosive. Intravenously Nitroglycerin is  administered with a severe attack of angina, acute myocardial infarction, and  acute heart failure. 
Friday, June 3, 2011
BE and Double Contrast Barium Enema
Fentanyl (stimulates mainly tsretseptor) is 100 times more active than  morphine, ie, used in doses that are 100 times less than morphine. The highest  daily dose of paracetamol - 4 in case of overdose paracetamol is the possibility  of severe liver damage (necrosis) because of the toxic metabolite of paracetamol  - Natsetilpbenzohinonimina (at therapeutic doses of paracetamol, this metabolite  is rapidly inactivated by glutathione). Therefore they are here  agonistamiantagonistami opioid receptors. Methadone is used to order replacement  therapy in the treatment of drug dependence to opioids. Analgesic effects,  sufficient to for short surgical procedures, providing ketamine (ketalar), which  blocks the receptors of excitatory amino acids (NMDApetseptor). To accelerate  the elimination of morphine from organism used forced diuresis or peritoneal  dialysis. a2Adrenomimetik clonidine (clonidine), reduces pain, arraign due to  stimulation adrenoretseptor and enhance descending inhibitory influences on the  conduct pain impulses in the spinal afferent paths brain. As a result, when  using heroin euphoria develops faster and more pronounced than with morphine.  Therefore, heroin can cause particularly severe drug dependence. In most  countries, the use of this drug is prohibited. Length of fentanyl 20-30 min.  Codeine may be effective in acute infectious diarrhea. The drug has about 2 pm  If necessary, naloxone administered repeatedly. In contrast, morphine omnopon  does not cause spasm of smooth muscles, as it contains alkaloids of isoquinoline  series - papaverine and nartsein having myotropic inflammatory properties. In here  with a pronounced depressant effect of fentanyl on the respiratory center can  the need for mechanical ventilation. Methadone works weaker, but the duration of  morphine arraign by mouth. Morphine content is omnopone 48-50%. In case of deep  respiratory depression have resorted to artificial ventilation. On analgesic  effect of morphine is inferior. Droperidol: potentiates the analgesic effect of  fentanyl, eliminates the patients anxiety, fear, anxiety, promoting the  development of indifference to surroundings, including those for surgery (state  neyrolepsii). Naloxone is administered intravenously or intramuscularly in cases  of poisoning opioid analgesics. Eliminate respiratory depression,  eyforiziruyuschee effect and other effects of opioid analgesics. Due to the high  content of morphine omnopon applied for the same indications as morphine. When  the pain associated with spasm of smooth muscles, such as kidney and liver  colic, omnopon has an advantage over morphine. arraign drug was appointed  interior, injected subcutaneously, intramuscularly or intravenously. When  trigeminal neuralgia, which is usually accompanied by bouts of severe pain, are  effective blockers of sodium channels of carbamazepine (tegretol, finlepsin) and  phenytoin (diphenine), as well as agonist arraign GAMKvretseptorov Gastric Ulcer depressant effect on the  selection of mediators from primary afferents). As an analgesic and antitussive  used as dihydrocodeine. Stimulates the reduction of the myometrium. Stimulate  oretseptor (sigmaretseptor), and therefore the their application can be  dysphoria, hallucinations, tachycardia, increased blood pressure. Baclofen is  also effective in phantom pains. Has a weak inflammatory properties. To  preparations containing morphine, is omnopon (Pantopon) - mixture of 5 arraign  in opium (morphine and codeine, papaverine, nartsein, thebaine). When headache,  migraine, neuralgia, arthralgia, myalgia, algodismenoree used Heart  Rate (acetaminophen, Panadol), arraign reduces pain due to the inhibition of  cyclooxygenase in the CNS. combined with neuroleptic droperidolom (combined drug  - talamonal) fentanyl is used for neyroleptanalgezii (Method of pain relief with  preserved consciousness during surgery). For reduce the toxicity of this  compound is used acetylcysteine (intravenous or oral), methionine (inside).  Trimeperidin contraindicated in respiratory depression. However, fentanyl is  more effective morphine arraign eliminates the pain of lack of effectiveness of  morphine. Pronounced analgesic properties have nitrous oxide, which is used by  inhalation for pain relief myocardial infarction in the postoperative period for  labor analgesia. Inferior to morphine in analgesic efficacy, less respiratory  depression, less dangerous with regard to drug dependence.   
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